Kelly Harkins (CEO, Claret Bioscience and Astrea Forensics): "Get more from less: The SRSLY sequencing preparation method"
In this webinar, Jordan Cheng (UCLA, School of Dentistry) describes the development of an extraction methods to capture highly degraded cell-free DNA from urine and plasma. A new class of cfDNA called ultra-short cell-free DNA are retained by this method and provides improved insights to the origin of cfDNA.
In this first-talk of the webinar series, Ms. Adrienne Chang (Cornell University) talks about the challenges in metagenomic assays from cfDNA. She highlights utility of single-stranded library preparation such as SRSLY in retaining short fragments and improving overall quality of the data obtained from difficult to sequence DNA inputs